NitroMist® Nitroglycerin Lingual Aerosol 400 mcg/spray


This item requires a completed License Authorization Form (LAF). Learn More.

This item requires a completed
License Authorization Form (LAF).
Learn More.
Your Price: $237.99
Additional Price:


* Hazardous Item - can only be shipped via Ground.

NitroMist® is a nitrate vasodilator indicated for acute relief of an attack or acute prophylaxis of angina pectoris due to coronary artery disease. Available in a 90 (4.1 gram) and 230 (8.5 gram) metered aerosol spray bottle.


  • The NitroMist Aerosol Delivery System: NitroMist has a unique aerosol delivery system that maintains the potency and stability of nitroglycerin for up to 36 months (or approximately 230 sprays).
  • Consistent Metered Dose: NitroMist features a unique delivery system. With each spray, a consistent metered dose is delivered via propellant-driven ultrafine mist. Adequate pressure must be applied to the actuator button to receive the full dose. Unit must be primed prior to initial use.
  • Priming NitroMist: After receiving a new prescription or refill, patients should remove the plastic cap, place forefinger on actuator button, and press 10 times. NitroMist is now primed for 6 weeks and ready to use. If not used for more than 6 weeks, the NitroMist bottle can be adequately reprimed with 2 sprays.
  • NitroMist Works Fast: NitroMist is rapidly absorbed to help provide fast relief. In one study, nitroglycerin aerosol spray provided symptom relief from acute angina in 60 seconds or less in 70% of patients vs. 38% for tablets (P<.001).1* In another large scale study of nearly 800 angina patients, nitroglycerin spray provided rapid symptom relief in most patients—regardless of age.2*†
  • Get Fast Protection: NitroMist also prevents angina that is triggered by exercise. Patients treated with NitroMist significantly increased their exercise tolerance (the time it takes to experience angina symptoms while exercising).3 Patients can take NitroMist 5 to 10 minutes before engaging in activities that may trigger an attack. NitroMist can be sprayed on or under the tongue during an angina attack and is not to be inhaled.
  • Convenient and Reliable: The NitroMist bottle is distinct. The pocket-sized bottle provides convenience and reliability, remaining potent for up to 36 months. It requires initial priming of 10 sprays and remains adequately primed for 6 weeks. If not used within 6 weeks, NitroMist can be adequately reprimed with 2 sprays. For complete instructions, watch the How to Take NitroMist patient video.


  • Storage temperature range: 15 to 30°C (59 to 86°F)


    • NDC: 76299-430-04
    • NDC: 76299-430-08

Per Federal Law, all of the items listed on this webpage are prescription drugs and/or devices. Before your account can receive these items, we must have a completed License Authorization Form (LAF) Form on file signed by your Medical Director. Orders from individuals will not be accepted.

*Study was conducted with an earlier version of nitroglycerin aerosol spray containing a CFC propellant.

†65% of patients <65 experienced symptom relief in 60 seconds or less when treated with spray vs. 34% with tablets. 57% of patients ≥65experienced symptom relief in 60 seconds or less when treated with spray vs. 36% with tablets.

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Exceptions to this policy would include all orders with special shipping requests (i.e. Next Day Air, etc.), orders for dealers/resellers, orders under $175.00 and all orders outside the contiguous United States. In addition, there is a $10.50 Narcotic Handling Fee on all narcotic orders.  Also, there is a $13.95 Refrigeration Handling Fee on all refrigerated medication shipments due to special requirements.

*Exceptions apply. See details.